syrona: Stratified Prevalence Comparison Across OMOP CDM Datasets

Derives stratified prevalence tables from the condition, procedure, and drug records in OMOP CDM (Observational Medical Outcomes Partnership Common Data Model) databases, computes log2 prevalence ratios between paired datasets, and synthesizes them via random-effects meta-analysis at multiple aggregation levels (year, age group, and sex). Between-study variance is estimated with the Paule-Mandel method, as described in Paule and Mandel (1982) <doi:10.6028/jres.087.022>.

Version: 0.2.1
Depends: R (≥ 4.1.0)
Imports: dplyr (≥ 1.1.0), dbplyr (≥ 2.3.0), DBI (≥ 1.2.0), CDMConnector (≥ 2.0.0), omopgenerics (≥ 1.3.0), tibble, tidyr, cli, rlang, shiny, ggplot2, ggiraph, ggtext, scales, grDevices, stats, readr (≥ 2.0.0), meta (≥ 6.0.0)
Suggests: testthat (≥ 3.0.0), duckdb (≥ 0.9.0), RPostgres, CohortConstructor (≥ 0.6.0), DT, shinycssloaders, knitr, rmarkdown
Published: 2026-09-04
DOI: 10.32614/CRAN.package.syrona
Author: Maarja Pajusalu [aut, cre]
Maintainer: Maarja Pajusalu <maarja.pajusalu at ut.ee>
BugReports: https://github.com/HealthInformaticsUT/Syrona/issues
License: MIT + file LICENSE
URL: https://github.com/HealthInformaticsUT/Syrona
NeedsCompilation: no
Language: en-US
Materials: README, NEWS
CRAN checks: syrona results

Documentation:

Reference manual: syrona.html , syrona.pdf
Vignettes: a00_introduction (source, R code)
a01_extraction (source, R code)
a02_comparison (source, R code)
a03_cohorts (source, R code)
a04_walkthrough (source, R code)

Downloads:

Package source: syrona_0.2.1.tar.gz
Windows binaries: r-devel: syrona_0.2.1.zip, r-release: not available, r-oldrel: syrona_0.2.1.zip
macOS binaries: r-release (arm64): not available, r-oldrel (arm64): syrona_0.2.1.tgz, r-release (x86_64): syrona_0.2.1.tgz, r-oldrel (x86_64): syrona_0.2.1.tgz

Linking:

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